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Juan Mucci Selected Research

Chagas Disease (American Trypanosomiasis)

1/2021Trypanosoma cruzi Induces B Cells That Regulate the CD4+ T Cell Response.
1/2020Parasite-host glycan interactions during Trypanosoma cruzi infection: trans-Sialidase rides the show.
1/2019Metabolic Labeling of Surface Neo-sialylglyconjugates Catalyzed by Trypanosoma cruzi trans-Sialidase.
1/2019Molecular and antigenic characterization of Trypanosoma cruzi TolT proteins.
10/2017Next-generation ELISA diagnostic assay for Chagas Disease based on the combination of short peptidic epitopes.
4/2016Sialic Acid Glycobiology Unveils Trypanosoma cruzi Trypomastigote Membrane Physiology.
7/2015Towards High-throughput Immunomics for Infectious Diseases: Use of Next-generation Peptide Microarrays for Rapid Discovery and Mapping of Antigenic Determinants.
5/2015Trypanosoma cruzi trans-sialidase prevents elicitation of Th1 cell response via interleukin 10 and downregulates Th1 effector cells.
7/2006The trans-sialidase from Trypanosoma cruzi triggers apoptosis by target cell sialylation.
1/2005The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents.
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Juan Mucci Research Topics

Disease

13Chagas Disease (American Trypanosomiasis)
01/2021 - 03/2002
8Infections
01/2021 - 08/2002
1Leishmaniasis
10/2017
1Communicable Diseases (Infectious Diseases)
07/2015
1Persistent Infection
10/2006
1Thrombocytopenia (Thrombopenia)
01/2005

Drug/Important Bio-Agent (IBA)

6trans-sialidaseIBA
01/2020 - 03/2002
3N-Acetylneuraminic Acid (Sialic Acid)IBA
01/2020 - 01/2005
3EnzymesIBA
01/2019 - 01/2005
3Virulence Factors (Pathogenicity Factors)IBA
05/2015 - 01/2005
2AntibodiesIBA
01/2021 - 06/2006
2Peptides (Polypeptides)IBA
10/2017 - 07/2015
2EpitopesIBA
10/2017 - 07/2015
2VaccinesIBA
10/2017 - 07/2015
1interleukin-21 (interleukin 21)IBA
01/2021
1Polysaccharides (Glycans)IBA
01/2020
1Recombinant ProteinsIBA
01/2019
1GlycoconjugatesIBA
01/2019
1MucinsIBA
01/2019
1B-Lymphocyte Epitopes (B-Cell Epitope)IBA
10/2017
1Sialic AcidsIBA
04/2016
1Biomarkers (Surrogate Marker)IBA
07/2015
1OvalbuminIBA
05/2015
1Interleukin-2 (IL2)IBA
05/2015
1Interleukin-4 (Interleukin 4)IBA
05/2015
1Interferon-gamma (Interferon, gamma)IBA
05/2015
1Proteins (Proteins, Gene)FDA Link
06/2014
1Interleukin-17 (Interleukin 17)IBA
05/2013
1MitogensIBA
10/2006
1CarboxypeptidasesIBA
09/2003